Psy-World

Close this window Factors influencing priority of criteria Criteria Particularly important in patients with these characteristics Short-term efficacy Severely depressed Long-term efficacy Repeat episodes Adverse effects Elderly, anxious Safety in overdose Suicidal, elderly Suicide risk Suicidal Drug interactions Elderly, physically ill, addicts Sexual dysfunction Sexaually active patient Withdrawal effects All, resistant patients (probability of switching) After determination of the priority of each criteria, a grid can be used to help effectively choose the mostly adapted antidepressant for a given patient. Criteria Importance of each criterion for this particular patient Properties of each antidepressant in relation to each criterion TCA1 TCA2 SSRI1 SSRI2 SSRI3 SNRI1 SNRI2 X Short-term efficacy +++ +++ ++ +++ Long-term efficacy + +++ ++ +++ Adverse effects + - - - + ++ Safety in overdose +++ - - - ++ ++ Suicide risk + 0 - - 0 Drug interactions +++ 0 - - - +++ Sexual dysfunction + - - - - ++ Withdrawal effects + 0 - - - +++ Close this window